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Genome Editing Initiative

The recent development of genome editing technology provides new methods to control eukaryotic genomes. Through funding from the University of Sydney Faculty of Science and the office of the Deputy Vice Chancellor we have recently obtained funds to develop and provide genome editing technologies for the University of Sydney. We are building a concentration of expertise and technical resources for genome editing housed in the Charles Perkins Center on the University of Sydney main campus. 

Our primary focus is to employ whole genome CRISPR screening to identify drug or disease mechanisms of action and/or identify new critical biological pathways. We are actively looking for collaborators that have a biological question that can be answered using large scale pooled or whole genome CRISPR applications.
 

 

Image 1: By Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute - http://www.ebi.ac.uk/pdbe-srv/view/images/entry/1wj9600.png, displayed on http://www.ebi.ac.uk/pdbe-srv/view/entry/1wj9/summary, Public Domain, https://commons.wikimedia.org/w/index.php?curid=6313219

Image 2: By Ben.lafrance - Template:Own rendition of the crystal structure solved by M Jinek et al, published in Science 2014, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=37224108