Our lab is focused on the systematic functional annotation of the genome. We combine genomic data (GWAS or sequencing) with high throughput CRISPR and/or RNAi screening to find critical regulators of biology. Our primary model systems are the fruit fly, human stem cells, and mice. The long-term objective of our research is to identify and characterize new genes and coding mutations that regulate human health and disease.
Currently we have a major focus on the genomics of chronic pain, however we have projects that relate to heart function, neurodegeneration, lifespan and metabolic disorders, kidney function, and cancer. Our interests are flexible and depend on the experience and interests of our team. In the end our goal is to rapidly improve patient treatment, and many of the new genes we have identified appear to be viable drug targets.
University of Sydney
The Neely Lab is based in the Charles Perkins Centre, which was completed in June 2014, and offers state-of-the-art facilities. The Neely Lab and the Charles Perkins Centre are affiliated with the University of Sydney's (USYD) Camperdown campus. USYD has over 50000 students spread across multiple campuses within Sydney, Australia. USYD was the first university to be established in Australia in the 1850’s and is currently ranked as the world’s 42nd most reputable university and its graduates are considered the 4th most employable in the world.*